Bayer Challenges India Compulsory License Ruling

German pharmaceutical company Bayer AG has formally lodged a challenge against a landmark Indian ruling that allowed a domestic generic drug-maker to produce a low-cost version of an anti-cancer drug for the Indian market. The appeal was filed on Friday 4 May with India’s Intellectual Property Appellate Board.

Back in March, the Indian Patent Office announced that it had issued its first compulsory license to Indian generic drug producer Natco - a move that effectively ended Bayer’s monopoly over Nexavar, a drug that is used to treat kidney and liver cancer.

Compulsory licensing is when a government authorises a party other than the patent owner to produce the patented product or process without the patent owner’s consent. The patent owner shall, nevertheless, be paid an adequate remuneration, taking into account the economic value of the authorisation.

The Indian ruling “damages the international patent system and endangers pharmaceutical research,” Pradhan added.

India is the world’s third-largest pharmaceutical drug producer by volume; in 2011 the domestic pharmaceutical market reached a record US$12.2 billion in sales.

New Delhi only began issuing patents for drugs in 2005 in order to comply with the WTO’s Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS Agreement). WTO rules explicitly allow compulsory licensing as long as procedures and conditions set out in Article 31 of TRIPS are fulfilled. The 2001 Doha Ministerial Declaration on the TRIPS Agreement and Public Health further recognised that “each member has the right to grant compulsory licences and the freedom to determine the grounds upon which such licences are granted.”

Original ruling

The Indian patent authority’s March ruling found Bayer’s version of Nexavar to be “exorbitantly priced and out of reach of most of the people.” The 62-page decision also indicated that the German pharmaceutical giant had not taken “adequate or reasonable steps to start the working of the invention in the territory of India on a commercial level and to an adequate extent.”

The ruling allows Natco to sell the drug at Rs. 8,800 per patient per month, or US$175 - a 97 percent price cut compared to Nexavar. The compulsory licence was granted to Natco until 2020; the Indian company is required to pay royalties to Bayer on a quarterly basis.

Compulsory licensing decision under scrutiny by trading partners

India’s landmark decision has not escaped the notice of its trading partners, with the Office of the US Trade Representative noting in an official report last week that it would “closely monitor developments concerning compulsory licensing of patents in India following the broad interpretation of Indian law in a recent decision … while also bearing in mind the Doha Declaration on TRIPS and Public Health.”

The Special 301 report, issued annually by the Office of the USTR, also urged New Delhi “to provide an effective system for protecting against unfair commercial use, as well as unauthorised disclosure, of test or other data generated to obtain marketing approval for pharmaceutical and agricultural chemical products.”

In the report, India was one of 13 countries placed on a “priority watch list” by Washington, a classification that indicates “significant concerns” in the area of intellectual property rights protection and enforcement.