Health Ministry Bans more than 300 Fixed Dose Combinations

[Ministry of Health and Family Welfare Notification [S.O. 705(E) to 1048(E)] dated 10^th March 2016]

On the basis of the recommendations of the Expert Committee and in exercise of powers conferred by Drugs and Cosmetics Act, 1940, the Central Government banned the manufacture for sale, sale and distribution for human use of fixed dose combination of around 344 drugs.

Central Government is satisfied that the use of the fixed dose combination of around 344 drugs is likely to involve risk to human beings whereas safer alternatives to the said combinations are available.

The matter has been examined by an Expert Committee appointed by the Central Government and the said Expert Committee recommended to the Central Government that the said drug is found to have no therapeutic justification.

On the basis of the recommendations of the said Expert Committee, the Central Government is satisfied that it is necessary and expedient in public interest to regulate by way of prohibition of manufacture for sale, sale and distribution for human use of the said drug in the country.

These ban formulations are included from big pharmaceutical companies like Pfizer, Abbott etc. And it will surely going to be biggest business hurdle for such companies.

Prior also health ministry banned medicines for number of times, but anyhow the ban had not be sustained for longer time. Now interesting to see whether these ban will be sustained and how industries reacts on it.

List of Banned Drugs are given below:

Fixed Dose Combinations of:

· Aceclofenac + Paracetamol + Rabeprazole

· Nimesulide + Diclofenac

· Nimesulide + Cetirizine + Caffein

· Nimesulide + Tizanidine

· Paracetamol + Cetirizine + Caffeine

· Diclofenac + Tramadol + Chlorzoxazone

· Dicyclomine + Paracetamol + Domperidone

· Nimesulide + Paracetamol dispersible tablets

· Paracetamol + Phenylephrine + Caffeine

· Diclofenac  + Tramadol  + Paracetamol

· Diclofenac + Paracetamol + Chlorzoxazone +famotidine

· Naproxen + Paracetamol

· Nimesulide + Serratiopeptidase

· Paracetamol + Diclofenac +famotidine

· Nimesulide + Pitofenone +fenpiverinium + Benzyl Alcohol

· Omeprazole + Paracetamol + Diclofenac

· Nimesulide  + Paracetamol injection

· Tamsulosin + Diclofenac

· Paracetamol + Phenylephrine + Chlorpheniramine + Dextromethorphan + Caffeine

· Diclofenac + Zinc Carnosine

· Diclofenac Sodium + Paracetamol + Chlorpheniramine Maleate + Magnesium Trisillicate

· Paracetamol + Pseudoephedrine + Cetrizine

· Phenylbutazone + Sodium Salicylate

· Lornoxicam + Paracetamol + Trypsin

· Paracetamol  + Mefenamic Acid  + Ranitidine + Dicyclomine

· Nimesulide + Dicyclomine

· Heparin + Diclofenac

· Glucosamine + Methyl Sulfonyl Methane + Vitamin D3 + Manganese + Boron + Copper + Zinc

· Paracetamol + Tapentadol

· Tranexamic Acid + Proanthocyanidin

· Benzoxonium Chloride + Lidocaine

· Lornoxicam + Paracetamol + Tramadol

· Lornoxicam + Paracetamol + Serratiopeptidase

· Diclofenac + Paracetamol + Magnesium Trisilicate

· Paracetamol + Domperidone + Caffeine

· Ammonium Chloride + Sodium Citrate + Chlorpheniramine Maleate + Menthol

· Paracetamol + Prochlorperazine Maleate

· Combikit of 3 tablets of Serratiopeptidase (enteric coated 20000 units) + Diclofenac Potassium & 2 tablets of Doxycycline

· Nimesulide + Paracetamol Suspension

· Aceclofenac + Paracetamol +famotidine

· Aceclofenac + Zinc Carnosine

· Paracetamol + Disodium Hydrogen Citrate + Caffeine

· Paracetamol + DL Methionine

· Disodium Hydrogen Citrate + Paracetamol

· Paracetamol + Caffeine + Codeine

· Aceclofenac (SR) + Paracetamol

· Diclofenac + Paracetamol injection

· Azithromycin + Cefixime

· Amoxicillin + Dicloxacillin

· Amoxicillin 250 mg + Potassium Clavulanate Diluted 62.5 mg

· Azithromycin + Levofloxacin

· Cefixime + Linezolid

· Amoxicillin + Cefixime + Potassium Clavulanic Acid

· Ofloxacin + Nitazoxanide

· Cefpodoxime Proxetil + Levofloxacin

· Combikit of Azithromycin, Secnidazole andfluconazole

· Levofloxacin + Ornidazole + Alpha Tocopherol Acetate

· Nimorazole + Ofloxacin

· Azithromycin + Ofloxacin

· Amoxycillin + Tinidazole

· Doxycycline + Serratiopeptidase

· Cefixime + Levofloxacin

· Ofloxacin + Metronidazole + Zinc Acetate

· Diphenoxylate + Atropine +furazolidonee

· Combikit of fluconazole Tablet, Azithromycin Tablet and Ornidazole Tablets

· Ciprofloxacin + Phenazopyridine

· Amoxycillin + Dicloxacillin + Serratiopeptidase

· Azithromycin + Cefpodoxime

· Lignocaine + Clotrimazole + Ofloxacin + Beclomethasone

· Cefuroxime + Linezolid

· Ofloxacin + Ornidazole + Zinc Bisglycinate

· Metronidazole + Norfloxacin

· Amoxicillin + Bromhexine

· Ciprofloxacin +fluticasone + Clotrimazole + Neomycin

· Metronidazole + Tetracycline

· Cephalexin + Neomycin + Prednisolone

· Azithromycin + Ambroxol

· Cilnidipine + Metoprolol Succinate + Metoprolol Tartrate

· L-Arginine + Sildenafil

· Atorvastatin + Vitamin D3 +folic Acid + Vitamin B12 + Pyridoxine

· Metformin + Atorvastatin

· Clindamycin + Telmisartan

· Olmesartan + Hydrochlorothiazide + Chlorthalidone

· L-5-Methyltetrahydrofolate Calcium + Escitalopram

· Pholcodine + Promethazine

· Paracetamol + Promethazine

· Betahistine + Ginkgo Biloba Extract + Vinpocetine + Piracetam

· Cetirizine + Diethyl Carbamazine

· Doxylamine + Pyridoxine + Mefenamic Acid + Paracetamol

· Drotaverine + Clidinium + Chlordiazepoxide

· Imipramine + Diazepam

· flupentixol + Escitalopram

· Paracetamol + Prochloperazine

· Gabapentin + Mecobalamin + Pyridoxine + Thiamine

· Imipramine + Chlordiazepoxide + Trifluoperazine + Trihexyphenidyl

· Chlorpromazine + Trihexyphenidyl

· Ursodeoxycholic Acid + Silymarin

· Metformin 1000/1000/500/500mg + Pioglitazone 7.5/7.5/7.5/7.5mg + Glimepiride 1/2/1/2mg

· Gliclazide 80 mg + Metformin 325 mg

· Voglibose+ Metformin + Chromium Picolinate

· Pioglitazone 7.5/7.5mg + Metformin 500/1000mg

· Glimepiride 1mg/2mg/3mg + Pioglitazone 15mg/15mg/15mg + Metformin 1000mg/1000mg/1000mg

· Glimepiride 1mg/2mg+ Pioglitazone 15mg/15mg + Metformin 850mg/850mg

· Metformin 850mg + Pioglitazone 7.5 mg + Glimepiride 2mg

· Metformin 850mg + Pioglitazone 7.5 mg + Glimepiride 1mg

· Metformin 500mg/500mg+Gliclazide SR 30mg/60mg + Pioglitazone 7.5mg/7.5mg

· Voglibose + Pioglitazone + Metformin

· Metformin + Bromocriptine

· Metformin + Glimepiride + Methylcobalamin

· Pioglitazone 30 mg + Metformin 500 mg

· Glimepiride + Pioglitazone + Metformin

· Glipizide 2.5mg + Metformin 400 mg

· Pioglitazone 15mg + Metformin 850 mg

· Metformin ER + Gliclazide MR + Voglibose

· Chromium Polynicotinate + Metformin

· Metformin + Gliclazide + Piogllitazone + Chromium Polynicotinate

· Metformin + Gliclazide + Chromium Polynicotinate

· Glibenclamide + Metformin (SR)+ Pioglitazone

· Metformin (Sustainded Release) 500mg + Pioglitazone 15 mg + Glimepiride 3mg

· Metformin (SR) 500mg + Pioglitazone 5mg

· Chloramphenicol + Beclomethasone + Clomitrimazole + Lignocaine

· Clotrimazole + Ofloxaxin + Lignocaine + Glycerine and Propylene Glycol

· Chloramphennicol + Lignocaine + Betamethasone + Clotrimazole + Ofloxacin + Antipyrine

· Ofloxacin + Clotrimazole + Betamethasone + Lignocaine

· Gentamicin Sulphate + Clotrimazole + Betamethasone + Lignocaine

· Clotrimazole + Beclomethasone + Ofloxacin + Lignocaine

· Becloemthasone + Clotrimazole + Chloramphenicol + Gentamycin + Lignocaine Ear drops

· flunarizine + Paracetamole + Domperidone

· Rabeprazole + Zinc Carnosine

· Magaldrate +famotidine + Simethicone

· Cyproheptadine + Thiamine

· Magaldrate + Ranitidine + Pancreatin + Domperidone

· Ranitidine + Magaldrate + Simethicone

· Magaldrate + Papain +fungul Diastase + Simethicone

· Rabeprazole + Zinc  + Domperidone

· famotidine + Oxytacaine + Magaldrate

· Ranitidine + Domperidone + Simethicone

· Alginic Acid + Sodium Bicarbonate + Dried Aluminium Hydroxide + Magnesium Hydroxide

· Clidinium + Paracetamol + Dicyclomine + Activated Dimethicone

· furazolidone + Metronidazole + Loperamide

· Rabeprazole + Diclofenac + Paracetamol

· Ranitidine + Magaldrate

· Norfloxacin+ Metronidazole + Zinc Acetate

· Zinc Carnosine + Oxetacaine

· Oxetacaine + Magaldrate +famotidine

· Pantoprazole (as Enteric Coated Tablet) + Zinc Carnosine (asfilm Coated Tablets)

· Zinc Carnosine + Magnesium Hydroxide + Dried Aluminium Hydroxide + Simethicone

· Zinc Carnosine + Sucralfate

· Mebeverine & Inner HPMC capsule (Streptococcusfaecalis + Clostridium butyricum + Bacillus mesentricus + Lactic Acid Bacillus)

· Clindamycin + Clotrimazole + Lactic Acid Bacillus

· Sildenafil + Estradiol Valerate

· Clomifene Citrate + Ubidecarenone + Zinc +folic Acid + Methylcobalamin + Pyridoxine + Lycopene + Selenium + Levocarnitine Tartrate + L-Arginine

· Thyroxine + Pyridoxine +folic Acid

· Gentamycin + Dexamethasone + Chloramphenicol + Tobramycin + Ofloxacin

· Dextromethorphan + Levocetirizine + Phenylephrine + Zinc

· Nimesulide + Loratadine + Phenylephrine + Ambroxol

· Bromhexine + Phenylephrine + Chlorepheniramine Maleate

· Dextromethorphan + Bromhexine + Guaiphenesin

· Paracetamol + Loratadine + Phenylephrine + Dextromethorphan + Caffeine

· Nimesulide + Phenylephrine + Caffeine + Levocetirizine

· Azithromycin + Acebrophylline

· Diphenhydramine + Terpine + Ammonium Chloride + Sodium Chloride + Menthol

· Nimesulide + Paracetamol + Cetirizine + Phenylephrine

· Paracetamol + Loratadine + Dextromethophan + Pseudoepheridine + Caffeine

· Chlorpheniramine Maleate + Dextromethorphan + Dextromethophan + Guaiphenesin + Ammonium Chloride + Menthol

· Chlorpheniramine Maleate + Ammonium Chloride + Sodium Citrate

· Cetirizine + Phenylephrine + Paracetamol + Zinc Gluconate

· Ambroxol + Guaiphenesin + Ammonium Chloride + Phenylephrine + Chlorpheniramine Maleate + Menthol

· Dextromethorphen + Bromhexine + Chlorpheniramine Maleate + Guaiphenesin

· Levocetirizine + Ambroxol + Phenylephrine  + Guaiphenesin

· Dextromethorphan + Chlorpheniramine + Chlorpheniramine Maleate

· Cetirizine + Ambroxol + Guaiphenesin + Ammonium Chloride + Phenylephrine + Menthol

· Chlorpheniramine + Phenylephrine + Caffeine

· Dextromethorphan + Triprolidine + Phenylephrine

· Terpinhydrate + Dextromethorphan + Menthol

· Dextromethorphan + Phenylephrine + Zinc Gluconate + Menthol

· Chlorpheniramine + Codeine + Sodium Citrate + Menthol Syrup

· Enrofloxacin + Bromhexin

· Bromhexine + Dextromethorphan + Phenylephrine + Menthol

· Levofloxacin + Bromhexine

· Levocetirizine + Ranitidine

· Levocetirizine + Phenylephrine + Ambroxol + Guaiphenesin + Paracetamol

· Cetirizine + Dextromethorphan + Phenylephrine + Zinc Gluconate + Paracetamol + Menthol

· Paracetamol + Pseudoephedrine + Dextromethorphan + Cetirizine

· Diphenhydramine + Guaiphenesin + Ammonium Chloride + Bromhexine

· Chlorpheniramine + Dextromethorphan + Phenylephrine + Paracetamol

· Dextromethorphen + Promethazine

· Diethylcabamazine Citrate + Cetirizine + Guaiphenesin

· Pseudoephedrine + Dextromethorphan + Cetirizine

· Chlorpheniramine + Phenylephrine + Dextromethophan + Menthol

· Ambroxol + Terbutaline + Dextromethorphan

· Dextromethorphan + Chlorpheniramine + Guaiphenesin

· Terbutaline + Bromhexine + Guaiphenesin + Dextromethorphan

· Dextromethorphan + Tripolidine + Phenylephirine

· Paracetamol + Dextromethorphan + Chlorpheniramine

· Pholcodine + Phenylephrine + Promethazine

· Codeine + Levocetirizine + Menthol

· Dextromethorphan + Ambroxol + Guaifenesin + Phenylephrine + Chlorpheniramine

· Cetirizine + Phenylephrine + Dextromethorphan + Menthol

· Roxithromycin + Serratiopeptidase

· Paracetamol + Phenylephrine + Triprolidine

· Acetaminophen + Loratadine + Ambroxol + Phenylephrine

· Cetirizine + Acetaminophen + Dextromethorphan + Phenyephrine + Zinc Gluconate

· Diphenhydramine + Guaifenesin + Bromhexine + Ammonium Chloride + Menthol

· Chlopheniramine Maleate + Codeine Syrup

· Cetirizine + Dextromethorphan + Zinc Gluconate + Menthol

· Paracetamol + Phenylephrine + Desloratadine + Zinc Gluconate + Ambroxol

· Levocetirizine + Montelukast + Acebrophylline

· Dextromethorphan + Phenylephrine + Ammonium Chloride + Menthol

· Dextromethorphan + Bromhexine + Guaiphenesin + Mentho

· Acrivastine + Paracetamol + Caffeine + Phenylephrine

· Naphazoline + Carboxy Methyl Cellulose + Menthol + Camphor + Phenylephrine

· Dextromethorphan + Cetirizine

· Nimesulide + Paracetamol + Levocetirizine + Phenylephrine + Caffeine

· Terbutaline + Ambroxol + Guaiphenesin + Zinc + Menthol

· Codeine + Chlorpheniramine + Alcohol Syrup

· Dextromethorphan + Phenylephrine + Guaifenesin + Triprolidine

· Ammomium Chloride + Bromhexine + Dextromethorphan

· Diethylcarbamazine + Cetirizine + Ambroxol

· Ethylmorphine + Noscapine + Chlorpheniramine

· Cetirizine + Dextromethorphan + Ambroxol

· Bromhexine + Dextromethorphan + Ammonium Chloride + Menthol

· Ambroxol + Guaifenesin + Phenylephrine + Chlorpheniramine

· Paracetamol + Phenylephrine + Chlorpheniramine + Zinc Gluconate

· Dextromethorphan + Phenylephrine + Cetirizine + Paracetamol + Caffeine

· fixed dose Dextromethophan + Chlorpheniramine + Guaifenesin + Ammonium Chloride

· Levocetirizine + Dextromethorphan + Zinc

· Paracetamol + Phenylephrine + Levocetirizine + Caffeine

· Chlorphaniramine + Ammonium Chloride + Sodium Chloride

· Paracetamol + Dextromethorphan + Bromhexine + Phenylephrine + Diphenhydramine

· Salbutamol + Bromhexine + Guaiphenesin + Menthol

· Chlorpheniramine + Ammonium Chloride + Noscapine + Sodium Citrate

· Cetirizine + Dextromethorphan + Bromhexine + Guaifenesin

· Diethyl Carbamazine + Chlorpheniramine + Guaifenesin

· Ketotifen + Cetirizine

· Terbutaline + Bromhexine + Etofylline

· Ketotifen + Theophylline

· Ambroxol + Salbutamol + Theophylline

· Cetririzine + Nimesulide + Phenylephrine

· Chlorpheniramine + Phenylephrine + Paracetamol + Zink Gluconate

· Acetaminophen + Guaifenesin + Dextromethorphan + Chlorpheniramine

· Cetirizine + Dextromethorphan + Phenylephrine + Tulsi

· Cetirizine + Phenylephrine + Paracetamol + Ambroxol + Caffeine

· Guaifenesin + Dextromethorphan

· Levocetirizine + Paracetamol + Phenylephirine + Caffeine

· Caffeine + Paracetamol + Phenylephrine + Chlorpheniramine

· Ketotifen + Levocetrizine

· Paracetamol + Levocetirizine + Phenylephirine + Zink Gluconate

· Paracetamol + Phenylephrine + Triprolidine + Caffeine

· Caffeine + Paracetamol + Phenylephrine + Cetirizine

· Caffeine + Paracetamol + Chlorpheniramine

· Ammonium Chloride + Dextromethorphan + Cetirizine + Menthol

· Dextromethorphan + Paracetamol + Cetirizine + Phenylephrine

· Chlorpheniramine + Terpin + Antimony Potassium Tartrate + Ammonium Chloride + Sodium Citrate + Menthol

· Terbutaline + Etofylline + Ambroxol

· Paracetamol + Codeine + Chlorpheniramine

· Paracetamol+Pseudoephedrine+Certirizine+Caffeine

· Chlorpheniramine+Ammonium Chloride + Menthol

· N-Acetyl Cysteine + Ambroxol + Phenylephrine + Levocertirizine

· Dextromethorphan + Phenylephrine + Tripolidine + Menthol

· Salbutamol + Certirizine + Ambroxol

· Dextromethorphan + Phenylephrine + Bromhexine + Guaifenesin + Chlorpheniramine

· Nimesulide + Certirizine + Phenylephrine

· Naphazoline + Chlorpheniramine + Zinc Sulphate + Boric Acid + Sodium Chloride + Chlorobutol

· Paracetamol + Bromhexine + Phenylephrine + Chlorpheniramine + Guaifenesin

· Salbutamol + Bromhexine

· Dextromethorphan + Phenylephrine + Guaifenesin + Certirizine + Acetaminophen

· Guaifenesin + Bromhexine + Chlorpheniramine + Paracetamol

· Chlorpheniramine + Ammonium Chloride + Chloroform + Menthol

· Salbutamol + Choline Theophylinate + Ambroxol

· Chlorpheniramine + Codeine Phosphate + Menthol Syrup

· Pseudoephedrine + Bromhexine

· Certirizine + Phenylephrine + Paracetamol + Caffeine + Nimesulide

· Dextromethorphan + Cetirizine + Guaifenesin + Ammonium Chloride

· Ambroxol + Salbutamol + Choline Theophyllinate + Menthol

· Paracetamol + Chlorpheniramine + Ambroxol + Guaifenesin + Phenylephrine

· Chlorpheniramine + Vasaka + Tolubalsm + Ammonium Chloride + Sodium Citrate + Menthol

· Bromhexine + Cetrizine + Phenylephrine IP+Guaifenesin + Menthol

· Dextromethorphan + Ambroxol + Ammonium Chloride + Chlorpheniramine + Menthol

· Dextromethorphan + Phenylephrine + Cetirizine + Zinc + Menthol

· Terbutaline + N-Acetyl L-Cysteine + Guaifenesin

· Calcium Gluconate + Levocetirizine

· Paracetamol + Levocetirizine + Pseudoephedrine

· Salbutamol + Choline Theophylinate + Carbocisteine

· Chlorpheniramine + Vitamin C

· Calcium Gluconate + Chlorpheniramine + Vitamin C

· Chlorpheniramine + Paracetamol + Pseudoephedrine + Caffeine

· Guaifenesin + Bromhexine + Chlorpheniramine + Phenylephrine + Paracetamol + Serratiopeptidase (as enteric coated granules) 10000 SP Units

· Paracetamol + Pheniramine

· Betamethasone +fusidic Acid + Gentamycin + Tolnaftate + lodochlorhydroxyquinoline (ICHQ)

· Clobetasol + Ofloxacin + Miconazole + Zinc Sulphat

· Clobetasole + Gentamicin + Miconazole + Zinc Sulphate

· Levocetirizine + Ambroxol + Phenylephrine + Paracetamol

· Permethrin + Cetrimide + Menthol

· Beclomethasone + Clotimazole + Neomycin + lodochlorohydroxyquinone

· Neomycin + Doxycycline

· Ciprofloxacin +fluocinolone + Clotrimazole + Neomycin + Chlorocresol

· Clobetasol + Ofloxacin + Ketoconazol + Zinc Sulphate

· Betamethasone + Gentamicin + Tolnaftate + lodochlorhydroxyquinoline

· Clobetasol + Gentamicin + Tolnaftate + lodochlorhydroxyquinone + Ketoconazole

· Allantoin + Dimethieone + Urea + Propylene + Glycerin + Liquid Paraffin

· Acriflavine + Thymol + Cetrimide

· Betamethasone + Neomycin + Tolnaftate + lodochlorohydroxyquinoline + Cholorocresol

· Clobetasol + Neomycin + Miconazole + Clotrimazole

· Ketoconazole + Tea Tree oil + Allantion + Zinc Oxide + Aloe Vera + Jojoba oil + Lavander oil + Soa noodels

· Clobetasol Propionate + Ofloxacin + Ornidazole + Terbinafine

· Clobetasol + Neomycin + Miconazole + Zinc Sulphate

· Beclomethasone Diproprionate + Neomycin + Tolnaftate + lodochlorhydroxyquinoline + Chlorocresol

· Betamethasone + Gentamycin + Zinc Sulphate + Clotrimoazole + Chlorocresol

· Borax + Boric Acid + Naphazoline + Menthol + Camphor + Methyl Hydroxy Benzoate

· Bromhexine + Dextromethorphan

· Dextromethophan + Chlopheniramine + Bromhexine

· Menthol + Anesthetic Ether

· Dextrometharphan + Chlopheniramine + Ammonium + Sodium Citrate + Menthol

· Ergotamine Tartrate + Belladona Dry Extarct+Caffeine + Paracetamol

· Phenytoin + Phenobarbitone

· Gliclazide 40mg + Metformin 400mg

· Paracetamol + Ambroxol + Phenylephrine + Chlorpheniramine

· Oflaxacin + Ornidazole Suspension

· Albuterol + Etofylline + Bromhexine + Menthol

· Albuterol + Bromhexine + Theophylline

· Salbutamol+Hydroxyethyltheophylline (Etofylline) + Bromhexine

· Paracetamol+Phenylephrine+Levocetirizine+Sodium Citrate

· Paracetamol + Propyphenazone + Caffeine

· Guaifenesin + Diphenhydramine + Bromhexine + Phenylephrine

· Dried Alumnium Hydroxie Gel + Prophantheline + Diazepam

· Bromhenxine + Phenylephrine + Chlorpheniramine + Paracetamol

· Beclomethasone + Clotrimazole + Gentamicin + lodochlorhydroxyquinoline

· Telmisartan + Metformin

· Ammonium Citrate + Vitamin B 12 +folic Acid + Zinc Sulphate

· Levothyroxine + Phyridoxine + Nicotinamide

· Benfotiamine + Metformin

· Thyroid + Thiamine + Riboflavin + Phyridoxine + Calcium Pantothenate + Tocopheryl Acetate + Nicotinamide

· Ascorbic Acid + Manadione Sodium Bisulphate + Rutin + Dibasic Calcium Phosphate + Adrenochrome mono Semicarbazone

· Phenylephrine + Chlorpheniramine + Paracetamol + Bromhexine + Caffeine

· Clotrimazole + Beclomethasone + Lignocaine + Ofloxacin + Acetic Aicd + Sodium Methyl Paraben + Propyl Paraben